Transactions
| Date | Player | Pos | Transactions |
| 10/16 | Keenan Reynolds | WR | pract. squad add |
| 10/15 | Jermaine Grace | LB | cut |
| 10/15 | Jermaine Grace | LB | off IR undisclosed |
| 10/13 | Tyrone Swoopes | TE | active/prac. squad |
| 10/13 | Keenan Reynolds | WR | cut |
| 10/9 | Tyrone Swoopes | TE | pract. squad add |
| 10/9 | Marcus Lucas | TE | pract. squad del |
| 10/3 | Maurice Alexander | S | signed |
| 10/3 | T.J. Green | S | signed |
| 10/3 | Darrell Daniels | TE | active/prac. squad |
| 10/3 | Kalan Reed | CB | pract. squad add |
| 10/2 | Mychal Kendricks | LB | suspended indefinitely (NFL Personal Conduct) |
| 10/2 | Khalid Hill | RB | cut |
| 10/2 | Khalid Hill | RB | off IR undisclosed |
| 10/2 | Will Dissly | TE | on IR torn patellar tendon |
| 10/2 | Earl Thomas | S | on IR broken left leg |
| 9/27 | Dontae Johnson | CB | cut |
| 9/27 | Darrell Daniels | TE | pract. squad add |
| 9/27 | Dontae Johnson | CB | off IR groin |
| 9/26 | Azeem Victor | LB | pract. squad add |
| 9/25 | Branden Jackson | DE | active/prac. squad |
| 9/25 | Darrell Daniels | TE | cut |
| 9/25 | Marcus Henry | C | pract. squad del |
| 9/19 | Marcus Henry | C | pract. squad add |
| 9/18 | Lavon Coleman | RB | pract. squad add |
| 9/18 | Tre'von Johnson | LB | pract. squad del |
| 9/17 | Tom Johnson | DT | cut |
| 9/17 | Shalom Luani | S | active/prac. squad |
| 9/17 | Jermaine Grace | LB | on IR undisclosed |
| 9/14 | Tre'von Johnson | LB | pract. squad add |
| 9/14 | Lavon Coleman | RB | pract. squad del |
| 9/13 | Shalom Luani | S | pract. squad add |
| 9/13 | Mychal Kendricks | LB | signed One-year contract (through 2018) |
| 9/12 | Keenan Reynolds | WR | active/prac. squad |
| 9/11 | Shalom Luani | S | cut |
| 9/11 | Malik Turner | WR | pract. squad add |
| 9/11 | Simeon Thomas | CB | pract. squad add |
| 9/11 | Frank Herron | DT | pract. squad del |
| 9/8 | Simeon Thomas | CB | cut |
| 9/8 | Akeem King | CB | active/prac. squad |
| 9/8 | Earl Thomas | S | reinstated |
| 9/8 | Dontae Johnson | CB | on IR groin |
| 9/7 | Austin Davis | QB | cut |
| 9/7 | Byron Maxwell | CB | cut |
| 9/7 | Erik Walden | LB | cut |
| 9/7 | Austin Davis | QB | off IR undisclosed |
| 9/7 | Byron Maxwell | CB | off IR hip |
| 9/7 | Erik Walden | LB | off IR hip |
| 9/5 | Earl Thomas | S | reinstated |
| 9/5 | Branden Jackson | DE | pract. squad add |
| 9/5 | Antwione Williams | LB | pract. squad del |
| 9/5 | Earl Thomas | S | Exempt/Commissioner's Permission List |
| 9/5 | Amara Darboh | WR | on IR undisclosed |
| 9/3 | Alex McGough | QB | pract. squad add |
| 9/3 | Marcus Lucas | TE | pract. squad add |
| 9/3 | Lavon Coleman | RB | pract. squad add |
| 9/3 | Antwione Williams | LB | pract. squad add |
| 9/3 | Frank Herron | DT | pract. squad add |
| 9/3 | Elijah Nkansah | T | pract. squad add |
| 9/3 | Jermaine Grace | LB | acquired from waiver |
| 9/3 | J.D. McKissic | RB | on IR foot |
| 9/2 | Jordan Simmons | G | acquired from waiver |
| 9/2 | Simeon Thomas | CB | acquired from waiver |
| 9/2 | Rees Odhiambo | T | cut |
| 9/2 | Branden Jackson | DE | cut |
| 9/2 | Akeem King | CB | pract. squad add |
| 9/2 | Keenan Reynolds | WR | pract. squad add |
| 9/2 | Jordan Roos | G | pract. squad add |
| 9/2 | Caleb Scott | WR | pract. squad add |
| 9/2 | Ricky Ali'ifua | DE | on IR undisclosed |
| 9/2 | Emmanuel Beal | LB | on IR undisclosed |
| 9/2 | T.J. Mutcherson | S | on IR undisclosed |
| 9/1 | Darrell Daniels | TE | traded for WR Marcus Johnson |
| 9/1 | Shalom Luani | S | traded for 2019 seventh-round draft pick |
| 9/1 | D.J. Alexander | LB | cut |
| 9/1 | Elijah Battle | CB | cut |
| 9/1 | Isaiah Battle | T | cut |
| 9/1 | Willie Beavers | G | cut |
| 9/1 | Jeremy Boykins | CB | cut |
| 9/1 | Marvin Bracy | WR | cut |
| 9/1 | Kyle Carter | TE | cut |
| 9/1 | Josh Forrest | LB | cut |
| 9/1 | Cyril Grayson Jr. | WR | cut |
| 9/1 | Marcus Henry | C | cut |
| 9/1 | Gerald Holmes | RB | cut |
| 9/1 | Joey Ivie | DT | cut |
| 9/1 | Lorenzo Jerome | S | cut |
| 9/1 | Akeem King | CB | cut |
| 9/1 | Alex McGough | QB | cut |
| 9/1 | Daniel Marx | RB | cut |
| 9/1 | Skyler Phillips | G | cut |
| 9/1 | Jake Pugh | LB | cut |
| 9/1 | Trovon Reed | CB | cut |
| 9/1 | Keenan Reynolds | WR | cut |
| 9/1 | Jordan Roos | G | cut |
| 9/1 | Caleb Scott | WR | cut |
| 9/1 | Justin Stockton | RB | cut |
| 9/1 | Damore'ea Stringfellow | WR | cut |
| 9/1 | Tyrone Swoopes | TE | cut |
| 9/1 | Malik Turner | WR | cut |
| 9/1 | Mike Tyson | CB | cut |
| 9/1 | Clayton Wilson | TE | cut |
| 9/1 | Maurice Alexander | S | cut |
| 9/1 | Ed Dickson | TE | reserve/non football injury quadriceps, groin |
| 9/1 | Austin Davis | QB | on IR undisclosed |
| 9/1 | Jamarco Jones | T | on IR ankle |
| 9/1 | Byron Maxwell | CB | on IR hip |
| 9/1 | Erik Walden | LB | on IR hip |
| 8/30 | Jason Hall | LB | cut |
| 8/29 | Brett Hundley | QB | traded for 2019 sixth-round draft pick |
| 8/29 | Tyler Lockett | WR | re-signed Three-year extension (through 2021) |
| 8/26 | Tanner McEvoy | WR | cut |
| 8/26 | Daniel Marx | RB | signed |
| 8/20 | Jason Myers | K | cut |
| 8/20 | Jon Ryan | P | cut |
| 8/20 | Elijah Battle | CB | signed |
| 8/20 | Marvin Bracy | WR | signed |
| 8/17 | Marcus Smith II | LB | cut |
| 8/17 | Elijah Battle | CB | cut |
| 8/17 | Erik Walden | LB | signed/unrest FA |
| 8/17 | Justin Stockton | RB | signed |
| 8/14 | Avery Young | G | cut |
| 8/14 | Avery Young | G | off IR undisclosed |
| 8/12 | Jalston Fowler | RB | cut |
| 8/12 | Je'Ron Hamm | TE | cut |
| 8/12 | Jason Hall | LB | signed |
| 8/12 | Elijah Battle | CB | signed |
| 8/11 | Warren Long | LB | cut |
| 8/11 | Marcus Henry | C | signed |
| 8/8 | Marvin Bracy | WR | cut |
| 8/8 | Gerald Holmes | RB | signed |
| 8/7 | Khalid Hill | RB | on IR undisclosed |
| 8/6 | Lord Hyeamang | DT | cut |
| 8/6 | Je'Ron Hamm | TE | signed |
| 8/6 | Joey Ivie | DT | signed |
| 8/3 | Ricky Ali'ifua | DE | signed |
| 8/3 | Lord Hyeamang | DT | signed |
| 8/3 | Marcus Henry | C | cut |
| 8/3 | Eddy Wilson | DT | cut |
| 8/2 | Josh Forrest | LB | re-signed/unrest FA |
| 8/2 | Jeremy Boykins | CB | signed |
| 8/2 | Alex Carter | S | cut |
| 8/2 | Je'Ron Hamm | TE | cut |
| 8/2 | Avery Young | G | on IR undisclosed |
| 8/1 | J.R. Sweezy | G | signed |
| 7/30 | Lorenzo Jerome | S | signed |
| 7/30 | Josh Perry | LB | retired |
| 7/29 | Kayaune Ross | WR | cut |
| 7/29 | Malik Turner | WR | signed |
| 7/28 | Tanner Carew | LB | cut |
| 7/28 | Marvin Bracy | WR | signed |
| 7/27 | Trovon Reed | CB | signed |
| 7/27 | Malik McDowell | DT | reserve/non football injury |
| 7/26 | Kam Chancellor | S | Placed on PUPL neck |
| 7/26 | DeAndre Elliott | CB | cut |
| 7/26 | Kayaune Ross | WR | signed |
| 7/26 | Je'Ron Hamm | TE | signed |
| 7/26 | Kyle Carter | TE | acquired from waiver |
| 7/26 | Earl Thomas | S | reserve/DNR |
| 6/20 | Rasheem Green | DE | signed/draft choice Four-year contract (through 2021) |
| 6/13 | Austin Calitro | LB | signed |
| 6/13 | Dadi Nicolas | LB | cut |
| 6/12 | Josh Perry | LB | signed |
| 6/12 | Nick Callender | T | cut |
| 5/30 | Marcus Martin | DE | cut |
| 5/29 | Brandon Marshall | WR | signed One-year contract (through 2018) |
| 5/17 | Keenan Reynolds | WR | signed |
| 5/17 | Dadi Nicolas | LB | signed |
| 5/17 | Noble Nwachukwu | DE | cut |
| 5/17 | Marcell Frazier | DE | cut |
| 5/17 | Shaquem Griffin | LB | signed/draft choice Four-year contract (through 2021) |
| 5/17 | Tre Flowers | CB | signed/draft choice Four-year contract (through 2021) |
| 5/16 | Rashaad Penny | RB | signed/draft choice Four-year contract (fifth-year option) |
| 5/15 | Jamarco Jones | T | signed/draft choice Four-year contract (through 2021) |
| 5/15 | Alex McGough | QB | signed/draft choice Four-year contract (through 2021) |
| 5/14 | Clayton Wilson | TE | signed |
| 5/11 | Stephen Morris | QB | cut |
| 5/7 | Damore'ea Stringfellow | WR | signed |
| 5/7 | T.J. Mutcherson | S | signed |
| 5/7 | Marcus Henry | C | signed |
| 5/7 | Nick Callender | T | signed |
| 5/7 | Avery Young | G | signed |
| 5/7 | Ka'Raun White | WR | cut |
| 5/7 | Taj Williams | WR | cut |
| 5/7 | Jason Hall | LB | cut |
| 5/7 | Paul Dawson | LB | cut |
| 5/7 | Brad Lundblade | C | cut |
| 5/4 | Cliff Avril | DE | cut |
| 5/4 | Ka'Raun White | WR | signed |
| 5/4 | Caleb Scott | WR | signed |
| 5/4 | Taj Williams | WR | signed |
| 5/4 | Marcus Martin | DE | signed |
| 5/4 | Khalid Hill | RB | signed |
| 5/4 | Emmanuel Beal | LB | signed |
| 5/4 | Jason Hall | LB | signed |
| 5/4 | Tanner Carew | LB | signed |
| 5/4 | Warren Long | LB | signed |
| 5/4 | Jake Pugh | LB | signed |
| 5/4 | Marcell Frazier | DE | signed |
| 5/4 | Eddy Wilson | DT | signed |
| 5/4 | Brad Lundblade | C | signed |
| 5/4 | Skyler Phillips | G | signed |
| 5/4 | Poona Ford | DT | signed |
| 5/4 | Will Dissly | TE | signed/draft choice Four-year contract (through 2021) |
| 5/4 | Michael Dickson | P | signed/draft choice Four-year contract (through 2021) |
| 5/4 | Jacob Martin | LB | signed/draft choice Four-year contract (through 2021) |
| 4/27 | Byron Maxwell | CB | re-signed/unrest FA One-year contract (through 2018) |
| 4/16 | Austin Davis | QB | re-signed/unrest FA One-year contract (through 2018) |
| 4/16 | Paul Dawson | LB | re-signed/unrest FA One-year contract (through 2018) |
| 4/16 | Joey Hunt | C | re-signed/excl. FA One-year tender (through 2018) |
| 4/16 | Branden Jackson | DE | re-signed/excl. FA One-year tender (through 2018) |
| 4/16 | Tyler Ott | TE | re-signed/excl. FA One-year tender (through 2018) |
| 4/13 | Stephen Morris | QB | signed |
| 4/13 | J.D. McKissic | RB | re-signed/excl. FA One-year tender (through 2018) |
| 4/13 | Sebastian Janikowski | K | signed/unrest FA One-year contract (through 2018) |
| 4/12 | Dion Jordan | DE | re-signed/rest FA One-year tender (through 2018) |
| 4/11 | Dontae Johnson | CB | signed/unrest FA One-year contract (through 2018) |
| 4/11 | Quinton Jefferson | DT | re-signed/excl. FA One-year tender (through 2018) |
| 3/28 | Justin Coleman | CB | re-signed/rest FA One-year contract (through 2018) |
| 3/27 | Trevone Boykin | QB | cut |
| 3/26 | Shamar Stephen | DT | signed/unrest FA One-year contract (through 2018) |
| 3/23 | Tom Johnson | DT | signed/unrest FA One-year contract (through 2018) |
| 3/23 | Marcus Smith II | LB | re-signed/unrest FA One-year contract (through 2018) |
| 3/22 | Mike Davis | RB | re-signed/unrest FA One-year contract (through 2018) |
| 3/20 | D.J. Fluker | G | signed/unrest FA One-year contract (through 2018) |
| 3/17 | Maurice Alexander | S | signed/unrest FA One-year contract (through 2018) |
| 3/16 | Barkevious Mingo | LB | signed/unrest FA Two-year contract (through 2019) |
| 3/16 | Ed Dickson | TE | signed/unrest FA Three-year contract (through 2020) |
| 3/16 | Akeem King | CB | signed One-year contract (through 2018) |
| 3/16 | Jaron Brown | WR | signed/unrest FA One-year contract (through 2018) |
| 3/14 | Marcus Johnson | WR | traded w/ pick for DE Michael Bennett and pick |
| 3/14 | Oday Aboushi | G | Declared Free Agent |
| 3/14 | Austin Davis | QB | Declared Free Agent |
| 3/14 | Terence Garvin | LB | Declared Free Agent |
| 3/14 | Jimmy Graham | TE | Declared Free Agent |
| 3/14 | Luke Joeckel | G | Declared Free Agent |
| 3/14 | Eddie Lacy | RB | Declared Free Agent |
| 3/14 | Byron Maxwell | CB | Declared Free Agent |
| 3/14 | Paul Richardson Jr. | WR | Declared Free Agent |
| 3/14 | Sheldon Richardson | DT | Declared Free Agent |
| 3/14 | Marcus Smith II | LB | Declared Free Agent |
| 3/14 | Matt Tobin | T | Declared Free Agent |
| 3/14 | Blair Walsh | K | Declared Free Agent |
| 3/14 | Michael Wilhoite | LB | Declared Free Agent |
| 3/14 | Luke Willson | TE | Declared Free Agent |
| 3/14 | Mike Davis | RB | Declared Free Agent |
| 3/14 | Paul Dawson | LB | Declared Free Agent |
| 3/14 | Josh Forrest | LB | Declared Free Agent |
| 3/14 | Christian French | DE | Declared Free Agent |
| 3/14 | Dewey McDonald | LB | Declared Free Agent |
| 3/14 | Thomas Rawls | RB | Declared Free Agent |
| 3/14 | Jordan Simone | S | Declared Free Agent |
| 3/14 | Garrison Smith | DT | Declared Free Agent |
| 3/14 | Tyrus Thompson | T | Declared Free Agent |
| 3/14 | Justin Coleman | CB | Restricted Free Agent |
| 3/14 | Dion Jordan | DE | Restricted Free Agent |
| 3/12 | Bradley McDougald | S | re-signed Three-year contract (through 2020) |
| 3/12 | Deshawn Shead | CB | cut |
| 3/9 | Richard Sherman | CB | cut |
| 3/9 | Jeremy Lane | CB | cut |
Last updated Oct. 22, 1:10 A.M. ET
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